Letter: Analysis of hemoglobin aggregation from Gibbs-Donnan equilibrium experiments.
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Letter: Analysis of hemoglobin aggregation from Gibbs-Donnan equilibrium experiments
Dear Sir: Gary-Bobo and Solomon (1968, 1971) have employed Gibbs-Donnan equilibrium studies in the assessment o f the anomalous osmotic behavior o f the red cell. In these studies, the interpretation was based on thermodynamic equations for ideal solutions. During the course of recent investigations, we have found that it is necessary to consider the nonideal aspects o f concentrated hemoglobin...
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(The diagram gives, however, no indication of the hydrostatic pressure due to the liquid in the manometer tube, which is a necessary condition for equilibrium. For further details of the experiments Loeb's original papers and book s may be consulted.) AH and BH represent hydrogen electrodes; AK and BK, calomel electrodes connected to the solutions by saturated KC1. Loeb measured the potential d...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 1976
ISSN: 0022-1295,1540-7748
DOI: 10.1085/jgp.68.1.105